Kaivon Assani – BIOMEDICAL ENGINEER

ABOUT ME

I am interested in biomedical engineering, research, and device development. Some of my accomplishments include:

Developed complex 3D model assemblies including a 74 part TI-84 calculator
Optimized and established over 40 protocols including imaging, protein analysis, and qPCR
Enhanced efficiency for an imaging from a procedure taking 30 hours to 5 hours by developing a macro in ImageJ
Collaborated with team to create, test and print a 3D model of the femoral hip implant, then present findings
Created 2 biomedical engineering organizations and founded the first annual biomedical research conference at WSU
Received many awards, published 4 first author papers and contributed to 4 others

Complex assemblies creating all angles, contours, extrusions engravings and decals
Use of Tools, relationships, complex features, finite element analysis, mates, exploded view and animation

Developed an electrospinning device by using a syringe pump loaded with polymer and collector plate spaced 18cm with a 37kV voltage potential.
Drug loading into electrospun wound patch, testing incorporation via FTIR
Bioanalysis of drug effect using Microscopy, Live/Dead Assay and qPCR
Data Analysis of qPCR data using t-test finding significant decrease in macrophage M1 markers and increase in M2 markers due to drug treatment.

Applied Rule of Mixtures to determine porosity to simulate material properties of bone using Ti-6Al-4V in order to prevent stress shielding
Finite Element Analysis using Solidworks Simulator to determine displacement of the porous Ti-6Al-4V Sample

Graphical user interface (GUI) developed to compile, analysis and condense information from multiple Excel files.
Flow Chart describing data analysis was written using Microsoft Visio.

Tension testing on two unknown materials. Engineering stress and strain were plotted and material properties were determined using MATLAB including elastic modulus, toughness, yield stress, yield strain, ultimate strength, fracture stress, fracture strain and max percent elongation. These were used to uncover the unknown material identities as as HDPE and PET.
Three point bend testing of uncooked and cooked chicken bones showed that uncooked bones had a higher elastic modulus and lower ultimate strength than the cooked bones. This was because cooked bones denatures collagen which is responsible for the bones elasticity.
Viscoelaciticity using creep and relaxation testing of foam samples was determined using a Kelvin–Voigt model. This study examines the accumulation of stress on the spring loaded action of the foam and shows non-linear relationship between strain over time as well as stress over time.

Circuit design with varying compositions of resistors, capacitors, inductors, transistors, diodes and alternating or direct current power supply.
Labview software with NI myDAQ measurement and continuity testing including phase difference, frequency, voltage, resistance and current.
High pass and low pass filter design using operational amplifiers and examining cutoff frequency, gain, transfer function and cutoff frequency.
Bipolar junction transistors with PNP and NPN configuration used to make half-wave rectifiers, full wave rectifiers, amplifiers and digital logic systems including summing, difference, integrating and differentiating amplifiers, and examining voltage, resistance, current and forward barrier voltage.

Two-way ANOVA using Standard Least Squares and Effect Leverage examining price comparison between computer components listed on Amazon, Newegg and several other distributors showing that Amazon has the cheapest overall price
JMP by SAS and Excel used to conduct a t-test for qPCR cellular characterization of macrophages showing effective M1 to M2 conversion by treatment with Retinoic Acid loaded in a Pullulan/Gelatin nanofiber scaffold.
Graphpad Prism used to conduct Mann-Whitney and ANOVA used to examine how Interferon Gamma affects Cystic Fibrosis macrophage autophagy including analysis of CF patient demographics, qPCR and protein levels, protein/bacteria co-localization, LDH, and ELISA IL1B and IL-10 characterization.